Southern Sisters Cafe

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815 Hwy 61 N
Vicksburg, MS 39183

Phone: (601) 883-9900

Neighborhood: Vicksburg

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Popular Menu Items

• Oven Roasted Turkey Club $12.49
• Oven roasted turkey, provolone cheese, avocado, bacon, red onions, tomatoes, lettuce and pesto ranch on a butter croissant.
• Cheese Curds $12.99
• Served with caramel and sweet chili sauce.
• Loaded Fries $12.99
• Smothered in cheddar cheese topped with bacon, green onions and sour cream.
• French Dip $15.99
• Served with fries and a side of au jus.
• Pasta $16.99
• Grilled garlic chicken, sautéed portabella mushroom, garlic, shallots and bacon tossed in a white wine sauce. Substitute shrimp for an additional price. Gluten free pasta for an additional price.

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Reviews for Southern Sisters Cafe

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  5.0 stars - Based on 14 reviews

#52 out of 148 restaurants in Vicksburg

#1 of 3 Cafe in Vicksburg

5 star				14 reviews	100%
4 star				0 reviews	0%
3 star				0 reviews	0%
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1 star				0 reviews	0%

Top Reviews of Southern Sisters Cafe

06/28/2025 - Lilly C.
The food here reminded me of the comforting meals my Granny used to make, with generous portions and a warm, friendly atmosphere that made everyone feel like family. The service was quick and polite, the menu offered delicious Southern classics and daily specials that sell out fast, making it an ideal stop for a satisfying, home-cooked lunch.

10/04/2024 - Karen F.
Stopped by this charming eatery on our way back from NOLA and it truly exceeded my expectations. The home-cooked meals reminded me of the delicious dishes my Granny used to prepare. The friendly staff added a warm touch to the whole dining experience. Planning to make another pit stop here in the future.

11/10/2022 - June Davidson
Every thing I've ever gotten was great. And I buy pans of chicken and dressing every HOLIDAY and every ONE loves it. Thanks

04/11/2022 - MenuPix User
great southern, downhome cooking