Mary Lou's Cafe y Cocina Mexicana

3.7 review_stars 
 |
#645 out of 6509 restaurants in San Antonio
($$), Mexican
Hours today: 8:00am-3:00pm
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Location and Contact


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Location Icon 4405 McCullough
San Antonio, TX 78212
Phone Icon Phone: (210) 396-7909
Neighborhood Icon Neighborhood: San Antonio

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Hours

Open Today:
8:00am-3:00pm
Monday6:30am-9:00pm
Tuesday6:30am-9:00pm
Wednesday6:30am-9:00pm
Thursday6:30am-9:00pm
Friday6:30am-10:00pm
Saturday6:30am-10:00pm
Sunday8:00am-3:00pm

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Restaurant Details

Delivery
No

Payment
Credit Cards Accepted

Parking
Parking Lot

Good for Kids
Yes

Attire
Casual

Alcohol
Yes - Full Bar

Reservations
No

Cuisines:
Mexican

Price Point
$$

WiFi
Yes

Outdoor Seats
Yes

Restaurant Description

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Restaurant Photos

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Reviews for Mary Lou's Cafe y Cocina Mexicana

#645 out of 6509 restaurants in San Antonio
#82 of 1156 Mexican in San Antonio

Top Reviews of Mary Lou's Cafe y Cocina Mexicana

review_stars 06/14/2025 - Elva S.
Mary Lou's Cafe in San Antonio offers authentic Mexican dishes with flavorful options like menudo, barbacoa tacos, and lengua guisada, accompanied by warm and attentive service from Moses and his team. The atmosphere is relaxed and family-friendly, with homemade tortillas and a variety of menu specials that make it a worthwhile dining experience.

review_stars 05/02/2021 - Sandys L
$6.50 for 1 chalupa. Insane! Must be a record.


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